Desoto Homes for Sale

Welcome to DeSoto, Illinois—a charming small town nestled in the heart of Jackson County. Known for its warm community spirit and picturesque landscapes, DeSoto offers a unique blend of rural tranquility and modern convenience. With a population of just over 1,500 residents, this close-knit community is perfect for families and individuals seeking a peaceful lifestyle while still having access to nearby urban amenities.

DeSoto is conveniently located near major highways, making it easy to explore the surrounding areas, including the vibrant city of Carbondale and the stunning Shawnee National Forest. The town boasts a rich history and a variety of local parks, providing ample opportunities for outdoor recreation, picnics, and family gatherings. The community hosts several annual events that foster camaraderie and celebrate local culture.

For those looking to plant roots in this delightful town, there are a variety of homes for sale that cater to diverse tastes and budgets. Whether you’re seeking a cozy starter home, a spacious family residence, or a charming bungalow, DeSoto’s real estate market has something for everyone. Many of these homes feature beautiful yards, modern amenities, and proximity to local schools and parks, making them ideal for families and individuals alike.

Discover the beauty and warmth of DeSoto, Illinois, where home is more than just a place—it's a community. Explore the current homes for sale and find your perfect sanctuary in this enchanting town today!

Newest Desoto Homes for Sale

$124,900

2 Beds ⋅ 2 Baths ⋅ 12714206 MLS ⋅ NEW Status

Welcome to your new home sweet home. This home has been lovingly taken care of over the past forty eight years by the same owners but it is time to find new owners who will love it just as much. It has been well maintained over the years and while it does need some updates it has had some major upgrades as well for peace of mind such as a new roof in 2023 along with new plumbing and electrical in the past few months. The main level has a kitchen with dining room along with a living room and three bedrooms. One bedroom was used as a in home beauty salon, while the equipment is still there it would be easy to convert back to a bedroom or a spacious mud room! Downstairs you will find a large family room along with a utility room, a half bathroom and a bedroom that was previously a laundry room. Home also comes with an extra lot making for a large yard for pets, entertaining or kids! Come take a look and make this home your own today!

205 N Poplar Street, Desoto

$299,000

1 Beds ⋅ 2 Baths ⋅ 12667731 MLS ⋅ ACTIVE Status

Private Country Retreat on 8.24 Surveyed Acres Tucked away at the very end of a dead-end road and surrounded by mature trees on three sides, this private 8.24-acre surveyed property offers the perfect blend of seclusion, comfort, and convenience. Whether you're looking for a peaceful residence, hobby farm, equestrian property, or a lucrative Airbnb/short-term rental opportunity, this property checks all the boxes. Designed for easy living, the all-electric home features durable ceramic tile flooring throughout, low-E windows, newer roof and low-maintenance vinyl siding. The kitchen is beautifully appointed with granite countertops and a tile backsplash, while the spacious living room showcases an entire wall of windows overlooking the deck and picturesque acreage beyond. A Vermont Castings wood-burning stove provides warmth, character, and the ability to heat the entire home. The oversized primary suite offers a relaxing retreat with both a spa tub and separate shower. The walk-out basement provides incredible potential, with a fully finished bathroom and bonus room already completed, leaving the remaining space ready for your finishing touches. Enjoy breathtaking views from three separate decks positioned to capture every angle of the property. The partially fenced acreage includes pasture areas suitable for horses or other livestock, while abundant wildlife enhances the natural beauty and peaceful setting. Located just minutes from Walker's Bluff Casino & Resort, Crab Orchard Lake, Devils Kitchen, Lake Kincaid, Shawnee National Forest, wine trails, shopping, restaurants, and Southern Illinois University, this property offers the rare combination of privacy and accessibility. With its desirable location, scenic setting, and unique amenities, it would make an exceptional full-time residence, vacation getaway, or income-producing short-term rental. A rare opportunity to own a private Southern Illinois retreat with endless possibilities.

450 Clark School Road, Desoto

$19,900

3 Beds ⋅ 2 Baths ⋅ 12624350 MLS ⋅ ACTIVE Status

Auction Listing!! - Property in an online auction. All offers must be submitted through the property's listing on www.auction. com. The sale will be subject to a 5% buyer's premium pursuant to the Auction Terms and Conditions.3 bedroom, 1.5 bath home with a carport. This is a Fannie Mae/Homepath Property. Legal Description Issue - property is going to be sold as is with no title insurance. Hold Harmless required to be signed by all parties before entry.

402 E Logan Street, Desoto

$220,000

5 Beds ⋅ 2 Baths ⋅ 12587914 MLS ⋅ ACTIVE Status

Spacious ranch-style home with room to spread out! This 5 bedroom, 2 full bath home offers plenty of living space both inside and out. The kitchen was remodeled within the past three years and features modern updates including a dishwasher and ample cabinetry. A convenient laundry/mudroom adds everyday functionality. Recent improvements include new flooring throughout and a newer metal roof for long-term durability. Outside, enjoy a large front yard and an equally expansive fenced backyard, perfect for entertaining, pets, or outdoor activities. With generous space and recent updates, this home offers comfort, convenience, and room to grow.

103 Smith Drive, Desoto

$779,000

7 Beds ⋅ 5 Baths ⋅ EB460556 MLS ⋅ ACTIVE Status

253 Ween Road, Desoto

Start Your Search

The data relating to real estate for sale on this website comes in part from the Broker Reciprocity program of Midwest Real Estate Data LLC. Real Estate listings held by brokerage firms other than our company are marked with the MRED Broker Reciprocity logo or the Broker Reciprocity thumbnail logo (the MRED logo) and detailed information about them includes the names of the listing brokers. Some properties which appear for sale on this website may subsequently have sold and may no longer be available. The accuracy of all information, regardless of source, including but not limited to square footages and lot sizes, is deemed reliable but not guaranteed and should be personally verified through personal inspection by and/or with the appropriate professionals. The information being provided is for consumers personal, non-commercial use and may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing.

Copyright 2026 MRED LLC. All rights reserved.

Based on information submitted to the MLS Grid as of . All data is obtained from various sources and has not been, and will not be, verified by broker or MLS Grid. MRED supplied Open House information is subject to change without notice. All information should be independently reviewed and verified for accuracy. Properties may or may not be listed by the office/agent presenting the information.

NOTICE: Many homes contain recording devices, and buyers should be aware they may be recorded during a showing.

The Digital Millennium Copyright Act of 1998, 17 U.S.C. § 512 (the DMCA) provides recourse for copyright owners who believe that material appearing on the Internet infringes their rights under U.S. copyright law. If you believe in good faith that any content or material made available in connection with our website or services infringes your copyright, you (or your agent) may send us a notice requesting that the content or material be removed, or access to it blocked. Notices must be sent in writing by email to DMCAnotice@theMLSGRID.com.

The DMCA requires that your notice of alleged copyright infringement include the following information: (1) description of the copyrighted work that is the subject of claimed infringement; (2) description of the alleged infringing content and information sufficient to permit us to locate the content; (3) contact information for you, including your address, telephone number and email address; (4) a statement by you that you have a good faith belief that the content in the manner complained of is not authorized by the copyright owner, or its agent, or by the operation of any law; (5) a statement by you, signed under penalty of perjury, that the information in the notification is accurate and that you have the authority to enforce the copyrights that are claimed to be infringed; and (6) a physical or electronic signature of the copyright owner or a person authorized to act on the copyright owner’s behalf. Failure to include all of the above information may result in the delay of the processing of your complaint.

Some listings have been excluded from this website.